Ollila D W, Morton D L
John Wayne Cancer Institute, Saint John's Health Center, Santa Monica, California, USA.
Chest Surg Clin N Am. 1998 Feb;8(1):183-96.
Available data suggest that patients who have a limited number of pulmonary metastases may benefit from complete surgical resection if they have favorable prognostic features such as a long TDT and a long DFI. If a patient is not a surgical candidate because of radiographic evidence of extrapulmonary disease, a short TDT, or a short DFI, then concurrent or sequential biochemotherapy offers the best chance for a complete response and remission.
现有数据表明,肺转移灶数量有限的患者若具有如较长的无病间期(TDT)和较长的疾病进展时间(DFI)等良好的预后特征,可能从手术完全切除中获益。如果患者因存在肺外疾病的影像学证据、较短的无病间期或较短的疾病进展时间而不适合手术,那么同步或序贯生物化疗为实现完全缓解和病情缓解提供了最佳机会。