Bestetti R B, Bombonato R, Kato M, Caixe S H, Finzi L A, Muccillo G, Brasil J C
Hospital do Coração de Ribeirão Preto.
Arq Bras Cardiol. 1997 Jun;68(6):397-400.
To assess the efficacy of partial left ventriculectomy as a treatment for patients with end-stage heart failure.
From February to June 1995, 7 patients with end-stage heart failure underwent partial left ventriculectomy. Subsequently, patients underwent clinical evaluation every 2 months, and 2-dimensional echocardiography at the 6th and 12th months after cardiac surgery. All patients were given digitalis and diuretics at conventional doses, and captopril or enalapril at maximal tolerated doses.
Two (28%) patients died; 1 from cardiac arrhythmia associated with gastrointestinal hemorrhage, and the other suddenly. One (14%) patient developed an embolic cerebrovascular accident. Four (57%) patients were hospitalized for congestive heart failure; all of them had either decreased the daily dose of captopril or enalapril or discontinued the drugs by themselves. Twelve months after ventriculectomy, left ventricular ejection fraction values were greater and left ventricular diastolic dimension and functional class values lower than those found before cardiac operation.
Beneficial effects of partial left ventriculectomy are observed one year after the surgical procedure. This technique, therefore, can be useful for the treatment of patients with end-stage heart failure.
评估部分左心室切除术治疗终末期心力衰竭患者的疗效。
1995年2月至6月,7例终末期心力衰竭患者接受了部分左心室切除术。随后,患者每2个月进行一次临床评估,并在心脏手术后第6个月和第12个月进行二维超声心动图检查。所有患者均接受常规剂量的洋地黄和利尿剂治疗,并给予最大耐受剂量的卡托普利或依那普利。
2例(28%)患者死亡;1例死于与胃肠道出血相关的心律失常,另1例突然死亡。1例(14%)患者发生栓塞性脑血管意外。4例(57%)患者因充血性心力衰竭住院;他们均自行减少了卡托普利或依那普利的每日剂量或停药。心室切除术后12个月,左心室射血分数值升高,左心室舒张末期内径和心功能分级值低于心脏手术前。
部分左心室切除术后一年可观察到有益效果。因此,该技术可用于治疗终末期心力衰竭患者。