Link C, Eickernjäger S, Porstendörfer D, Averhoff B
Institut für Mikrobiologie und Genetik, Georg-August-Universität, Göttingen, Germany.
J Bacteriol. 1998 Mar;180(6):1592-5. doi: 10.1128/JB.180.6.1592-1595.1998.
A gene (comC) essential for natural transformation was identified in Acinetobacter sp. strain BD413. ComC has a typical leader sequence and is similar to different type IV pilus assembly factors. A comC mutant (T308) is not able to bind or take up DNA but exhibits a piliation phenotype indistinguishable from the transformation wild type as revealed by electron microscopy.
在不动杆菌属BD413菌株中鉴定出一个对自然转化至关重要的基因(comC)。ComC具有典型的前导序列,并且与不同的IV型菌毛组装因子相似。如电子显微镜所示,comC突变体(T308)无法结合或摄取DNA,但表现出与转化野生型难以区分的菌毛表型。