Yee D
University of Texas Health Science Center at San Antonio, 78284-7884, USA.
Breast Cancer Res Treat. 1998 Feb;47(3):197-9. doi: 10.1023/a:1005938615798.
In 1992, a special issue of Breast Cancer Research and Treatment was devoted to the insulin-like growth factors and breast cancer. In that issue, identification of the key components of the IGF system was reviewed and their potential role in breast cancer growth was described. In this issue, we revisit the IGF system with particular attention to data that further supports their role in the growth regulation of breast cancer. Several new facets of the IGF system are described, and several laboratories have more clearly defined how each individual component of the IGF system may influence breast cancer biology.
1992年，《乳腺癌研究与治疗》的一期特刊专门探讨了胰岛素样生长因子与乳腺癌。在那一期中，对IGF系统关键成分的识别进行了综述，并描述了它们在乳腺癌生长中的潜在作用。在本期中，我们再次审视IGF系统，特别关注进一步支持其在乳腺癌生长调节中作用的数据。文中描述了IGF系统的几个新方面，并且几个实验室更明确地界定了IGF系统的各个单独成分如何影响乳腺癌生物学。
