Axton J H, Garnett P A
S Afr Med J. 1976 Jun 26;50(27):1051-3.
Oral oxamniquine 800 mg/m2 body surface area/day in divided doses for 2 days, was given to 57 children with schistosomal infections. Haematological and biochemical tests suggest that this drug is safe, even in the presence of significant liver enlargement. Parasitological investigations in 32 children who were followed up for 1 month indicate that oxamniquine is effective in the treatment of S. mansoni infection, but that it has little effect on S. haematobium infection.
对57名血吸虫感染儿童给予口服奥沙尼喹，剂量为800毫克/平方米体表面积/天，分剂量服用，共2天。血液学和生化检查表明，即使存在明显肝脏肿大，该药物也是安全的。对32名随访1个月的儿童进行的寄生虫学调查表明，奥沙尼喹对曼氏血吸虫感染有效，但对埃及血吸虫感染几乎没有效果。
