罗得西亚口服奥沙尼喹的剂量探索试验。
Dose-finding trials of oral oxamniquine in Rhodesia.
作者信息
de V Clarke V, Blair D M, Weber M C, Garnett P A
出版信息
S Afr Med J. 1976 Oct 30;50(46):1867-71.
PMID:996687
Abstract
Oral oxamniquine at a total dose of 60 mg/kg (given in 4 equal doses morning and evening over 2 days, after food) is an efficient and apparently very safe drug for the treatment of Schistosoma mansoni infections. Lower doses, or shorter schedules of treatment, are less efficient. The drug has little or no effect on S. haematobium infections. Side-effects are mild and infrequent.
摘要
口服奥沙尼喹，总剂量为60毫克/千克（分4等份，早晚各1份，于2天内饭后服用），是治疗曼氏血吸虫感染的一种有效且显然非常安全的药物。较低剂量或较短疗程的治疗效果较差。该药物对埃及血吸虫感染几乎没有影响。副作用轻微且不常见。
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