劳伦分类法在胃癌化疗中的意义。

Significance of Laurén's classification in chemotherapy of gastric carcinoma.

作者信息

Kakizaki G, Fujiwara Y, Kato E, Saito T, Maeta T, Ishidate T, Ono I

出版信息

Tohoku J Exp Med. 1976 May;119(1):41-9. doi: 10.1620/tjem.119.41.

DOI:10.1620/tjem.119.41

Abstract

The effects of anticancer agents were studied on the basis of survival rates following surgery for gastric carcinomas in different histologic types of Laurén's classification. It was revealed that Laurén's classification would provide an index to the use of anticancer agents to a certain extent. Anticancer agents were effective against diffuse gastric carcinoma, and should therefore be intensively used for treatment of this malignancy. For female patients with diffuse gastric carcinoma, careful selection of adequate anticancer agents is highly necessary. Anticancer agents were less effective against intestinal-type carcinoma, and it would therefore be necessary to use anticancer agents on the aged male patients with this malignancy by taking his age and side effects of the agents into consideration.

摘要

根据劳伦分类法中不同组织学类型的胃癌手术后生存率，对抗癌药物的疗效进行了研究。结果显示，劳伦分类法在一定程度上可为抗癌药物的使用提供指标。抗癌药物对弥漫型胃癌有效，因此应大力用于治疗这种恶性肿瘤。对于弥漫型胃癌的女性患者，谨慎选择合适的抗癌药物非常必要。抗癌药物对肠型癌的疗效较差，因此对于患有这种恶性肿瘤的老年男性患者，有必要考虑其年龄和药物副作用来使用抗癌药物。