Digestive Health Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
The Esophageal and Swallowing Center, Digestive Health Center, MetroHealth Medical System, Division of Gastroenterology and Hepatology, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA.
Drugs Aging. 2019 Dec;36(12):1073-1081. doi: 10.1007/s40266-019-00708-2.
Gastroesophageal reflux disease (GERD) is an especially common disorder in the elderly population. Its presentation in this population is often different from that in younger patients. A greater proportion of patients experience atypical GERD symptoms rather than heartburn or regurgitation, increasing the likelihood the diagnosis will be missed or overlooked. Elderly patients more commonly present with severe erosive esophagitis and GERD complications compared with younger patients, and thus may require more aggressive therapy. While diagnostic work-up and management of GERD in elderly patients is similar to the general population and primarily involves acid suppression with endoscopic and surgical techniques reserved for refractory cases, there are many important considerations that are particular to the elderly.
胃食管反流病(GERD)在老年人群中尤为常见。其在该人群中的表现通常与年轻患者不同。更多的患者出现非典型 GERD 症状,而不是烧心或反流,这增加了漏诊或忽视的可能性。与年轻患者相比,老年患者更常出现严重的侵蚀性食管炎和 GERD 并发症,因此可能需要更积极的治疗。虽然老年患者 GERD 的诊断和治疗与一般人群相似,主要涉及使用内镜和手术技术抑制胃酸,但也有许多特别针对老年人的重要考虑因素。