Swithers S E, Martinson F A
Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 27907-1364, USA.
Behav Neurosci. 1998 Feb;112(1):213-24. doi: 10.1037//0735-7044.112.1.213.
The effects of repeated oral stimulation on ingestive responding were investigated in adult rats. A series of brief intraoral infusions of flavored diet was delivered to female rats once every minute through an oral cannula. When the flavor of the infused diet remained constant, significant decreases in mouthing behavior were observed by the end of testing, whereas switching the flavor of the diet during testing resulted in enhanced responding and infusions delivered through gastric cannulas produced minimal effects. Patterns of oral responding were also similar in food-restricted rats. These patterns of responding suggest that adult rats habituate to oral stimulation. Finally, oral habituation led to decreased ingestion, whereas gastric infusions had minimal effects. Thus, oral habituation may represent a mechanism influencing intake in rats at all ages.
在成年大鼠中研究了反复口腔刺激对摄食反应的影响。通过口腔插管每分钟向雌性大鼠进行一系列短暂的口腔内风味食物输注。当输注食物的味道保持恒定时，在测试结束时观察到舔嘴行为显著减少，而在测试过程中改变食物的味道则导致反应增强，并且通过胃插管进行的输注产生的影响最小。食物受限的大鼠的口腔反应模式也相似。这些反应模式表明成年大鼠会习惯口腔刺激。最后，口腔习惯化导致摄食量减少，而胃内输注的影响最小。因此，口腔习惯化可能是影响各年龄段大鼠摄入量的一种机制。
