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[骨合成植入物与术后早期感染:保留或取出材料的愈合情况?]

[The osteosynthesis implant and early postoperative infection: healing with or without removal of the material?].

作者信息

Hofmann G O, Bär T, Bühren V

机构信息

Berufsgenossenschaftliche Unfallklinik, Murnau/Staffelsee.

出版信息

Chirurg. 1997 Nov;68(11):1175-80. doi: 10.1007/s001040050341.

Abstract

This prospective study served as a quality control of a revision concept for case of post-traumatic infection following open reduction and internal fixation in fracture treatment. It is based on clinical and microbiological criteria and has two aims: (1) eradication of the infection and avoidance of development of chronic osteitis; (2) maintenance of internal fixation, if possible. Thirty-four patients were recruited in this study. Surgical revisions were performed according to a consistent concept (debridement, irrigation, local chemotherapy, drainage) in defined time intervals (2 days). The operation site had to be bacteriologically clean after four revisions. Otherwise, the implant had to be removed. Both aims were reached in 11 cases: management of infection with maintenance of internal fixation. In 23 cases the implant material had to be removed. Nevertheless the infection was eliminated in all these patients without exception. The following risk factors for mandatory implant removal were evaluated: diabetes, arteriosclerosis, alcoholism, nicotine. This revision concept helps in the management of acute postoperative osteitis following ORIF in fracture treatment and in avoiding the development of chronic osteitis.

摘要

这项前瞻性研究作为骨折治疗中切开复位内固定术后创伤后感染病例修订概念的质量控制。它基于临床和微生物学标准,有两个目标:(1)根除感染并避免慢性骨髓炎的发展;(2)尽可能维持内固定。本研究招募了34名患者。手术修订按照一致的概念(清创、冲洗、局部化疗、引流)在规定的时间间隔(2天)进行。经过四次修订后,手术部位必须在细菌学上保持清洁。否则,必须取出植入物。11例患者实现了两个目标:在维持内固定的情况下控制感染。23例患者必须取出植入物材料。然而,所有这些患者的感染均无一例外被消除。评估了以下必须取出植入物的风险因素:糖尿病、动脉硬化、酗酒、吸烟。这种修订概念有助于骨折治疗中切开复位内固定术后急性骨髓炎的管理,并避免慢性骨髓炎的发展。

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