乳腺癌死亡率的地区差异：较高的死亡率意味着发病率升高还是生存率降低？
Geographic variations in breast cancer mortality: do higher rates imply elevated incidence or poorer survival?
作者信息
Goodwin J S, Freeman J L, Freeman D, Nattinger A B
机构信息
Department of Medicine, University of Texas Medical Branch, Galveston, USA.
出版信息
Am J Public Health. 1998 Mar;88(3):458-60. doi: 10.2105/ajph.88.3.458.
Abstract
OBJECTIVES
Mortality rates from breast cancer are approximately 25% higher for women in the northeastern United States than for women in the South or West. This study examined the hypothesis that the elevation is due to decreased survival rather than increased incidence.
METHODS
Data on breast cancer incidence, treatment, and mortality were reviewed.
RESULTS
The elevated mortality in the Northeast is apparent only in older women. For women aged 65 years and older, breast cancer mortality is 26% higher in New England than in the South, while incidence is only 3% higher. Breast cancer mortality for older women by state correlates poorly with incidence (r = 0.28).
CONCLUSIONS
Those seeking to explain the excess breast cancer mortality in the Northeast should assess survival and should examine differences in cancer control practices that affect survival.
摘要
目的
美国东北部女性的乳腺癌死亡率比南部或西部女性高出约25%。本研究检验了这样一种假设，即死亡率升高是由于生存率降低而非发病率增加所致。
方法
对乳腺癌发病率、治疗和死亡率的数据进行了回顾。
结果
东北部死亡率升高仅在老年女性中明显。对于65岁及以上的女性，新英格兰地区的乳腺癌死亡率比南部高26%，而发病率仅高3%。按州划分的老年女性乳腺癌死亡率与发病率的相关性较差（r = 0.28）。
结论
那些试图解释东北部乳腺癌死亡率过高现象的人应该评估生存率，并研究影响生存率的癌症控制措施的差异。
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