Müller-Schimpfle M, Stoll P, Stern W, Huppert P E, Claussen C D
Abteilung für Radiologische Diagnositk, Eberhard-Karls-Univeristät Tübingen.
Rofo. 1998 Feb;168(2):195-9. doi: 10.1055/s-2007-1015208.
To develop and test a new technique for MR-guided localisation of breast lesions.
The examinations were performed on a 1.0 T imager in prone position, using a sagittally oriented oval spine coil. The localization device consisted of a perforated lateral plate which can be angulated. The plate contained an "M" shaped tube filled with oil. This enabled exact localization of the lesion in relation to the bore holes on the MR images. After needle placement through a sterile bushing, the 5 mm marking coil was placed through the needle adjacent to the lesion. Then a suspension of charcoal, Gd-DTPA, and water was injected. Suspicious lesions that could be visualised only by MR were localised preoperatively and marked in 6 patients.
The lesion size ranged from 0.5 to 3.5 cm (median 1.2 cm). Three benign lesions (intraductal hyperplasia twice, radial scar once) and three malignant lesions (ductal invasive cancer twice, DCIS once) were found. Angulation of the plate was beneficial in three cases.
With the new marking technique, exact MR-guided localization of breast lesions using an add-on device is feasible. Construction of an additional MR coil is not necessary. Excision of the lesion is proven by the concomitant excision of the marking coil.
开发并测试一种用于磁共振引导下乳腺病变定位的新技术。
检查在1.0 T成像仪上采用俯卧位进行，使用矢状面取向的椭圆形脊柱线圈。定位装置由一个可成角度的带孔侧板组成。该板包含一个填充油的“M”形管。这使得能够在磁共振图像上相对于钻孔精确地定位病变。通过无菌套管放置针后，将5毫米标记线圈通过针放置在病变附近。然后注射炭、钆喷酸葡胺和水的混悬液。6例仅通过磁共振成像才能显示的可疑病变在术前进行了定位并标记。
病变大小范围为0.5至3.5厘米（中位数1.2厘米）。发现3例良性病变（导管内增生2次，放射状瘢痕1次）和3例恶性病变（浸润性导管癌2次，导管原位癌1次）。在3例中，板的成角度是有益的。
采用新的标记技术，使用附加装置在磁共振引导下对乳腺病变进行精确的定位是可行的。无需构建额外的磁共振线圈。通过同时切除标记线圈可证实病变已被切除。
