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颞骨软骨肉瘤与耳硬化症

Chondrosarcoma of the temporal bone and otosclerosis.

作者信息

Ramírez-Camacho R, Pinilla M, Ramón y Cajal S, García Berrocal J R, Vicente J

机构信息

Otorhinolaryngology Service, Puerta de Hierro, Universidad Autónoma de Madrid, Spain.

出版信息

ORL J Otorhinolaryngol Relat Spec. 1998 Jan-Feb;60(1):58-60. doi: 10.1159/000027565.

Abstract

Chondrosarcoma constitutes 6% of all primary bone tumors and 11% of malignant primary bone tumors. Nevertheless, in a review of the tumor registry of the University of Michigan covering a period of 50 years, there were only 3 cases involving the temporal bone. A case of a woman with a chondrosarcoma of the temporal bone that was partially resected by means of an infratemporal approach at the skull base is presented. This patient had previously undergone surgical treatment for otosclerosis of the other ear. Several considerations regarding survival factors in this type of tumor are dealt with in terms of the histological features, therapeutic options and anatomic location. The possibility that this lesion may originate from the persistence of the cartilaginous inclusions that some authors consider to be involved in the origin of otosclerosis is discussed.

摘要

软骨肉瘤占所有原发性骨肿瘤的6%,占原发性恶性骨肿瘤的11%。然而,在对密歇根大学50年期间肿瘤登记处的回顾中,仅发现3例累及颞骨的病例。本文报告1例颞骨软骨肉瘤女性患者,采用颅底颞下入路进行了部分切除。该患者此前曾因另一侧耳朵的耳硬化症接受过手术治疗。本文从组织学特征、治疗选择和解剖位置等方面探讨了这类肿瘤生存因素的几个相关问题。文中还讨论了该病变可能起源于某些作者认为与耳硬化症起源有关的软骨包涵体持续存在的可能性。

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