Macsai M S, Gainer K M, Chisholm L
Department of Ophthalmology, West Virginia University, Robert C. Byrd Health Sciences Center, Morgantown 26506-9193, USA.
Cornea. 1998 Mar;17(2):129-34. doi: 10.1097/00003226-199803000-00002.
To report the use of perfluoropropane (C3F8) gas in the repair of Descemet's membrane detachments.
Descemet's membrane detachments after cataract surgery in three eyes and pars plana vitrectomy in a fourth underwent anterior-chamber gas-exchange descemetopexy with an isoexpansile 14% mixture of C3F8 to facilitate reattachment of Descemet's membrane.
Descemet's membrane detachment was successfully reattached after anterior-chamber gas exchange with 14% C3F8 in three of the four eyes treated. The fourth eye treated with 14% C3F8 probably failed Descemet's membrane reattachment because of an unrecognized viscoelastic bleb situated anterior to Descemet's membrane. No corneal decompensation or fluctuations in intraocular pressure were believed to be attributable to isoexpansile C3F8 gas exchange.
Early recognition and repair of Descemet's membrane detachments may prevent complications, such as corneal decompensation, corneal opacities and edema, and an overall decline in visual acuity. Isoexpansile C3F8 is demonstrated as a safe and efficacious alternative for the repair of Descemet's membrane detachment.
报告全氟丙烷（C3F8）气体在Descemet膜脱离修复中的应用。
三只白内障手术后发生Descemet膜脱离的眼睛以及第四只接受玻璃体切割术的眼睛，采用等膨胀性14% C3F8混合气体进行前房气体交换性Descemet膜固定术，以促进Descemet膜重新附着。
在接受治疗的四只眼睛中，三只眼睛在前房注入14% C3F8进行气体交换后，Descemet膜脱离成功重新附着。第四只接受14% C3F8治疗的眼睛，Descemet膜重新附着可能失败，原因是在Descemet膜前方存在未被识别的粘弹剂泡。未发现角膜失代偿或眼压波动与等膨胀性C3F8气体交换有关。
早期识别和修复Descemet膜脱离可预防并发症，如角膜失代偿、角膜混浊和水肿以及视力整体下降。等膨胀性C3F8被证明是修复Descemet膜脱离的一种安全有效的替代方法。
