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Clustering of nicotinic acetylcholine receptors: from the neuromuscular junction to interneuronal synapses.烟碱型乙酰胆碱受体的聚集:从神经肌肉接头到中间神经元突触
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The myristoylated protein rapsyn is cotargeted with the nicotinic acetylcholine receptor to the postsynaptic membrane via the exocytic pathway.肉豆蔻酰化蛋白rapsyn通过胞吐途径与烟碱型乙酰胆碱受体共同靶向至突触后膜。
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Postsynaptic clustering of gamma-aminobutyric acid type A receptors by the gamma3 subunit in vivo.体内γ-氨基丁酸A型受体通过γ3亚基进行突触后聚集。
Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12860-5. doi: 10.1073/pnas.96.22.12860.

本文引用的文献

1
Mechanism of nicotinic acetylcholine receptor cluster formation by rapsyn.rapsyn介导烟碱型乙酰胆碱受体簇形成的机制
Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4007-12. doi: 10.1073/pnas.95.7.4007.
2
Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1.油条蛋白,一种神经肌肉接头和大脑中的新型蛋白质,它与NMDA受体亚基NR1的特定剪接变体相互作用。
J Neurosci. 1998 Mar 15;18(6):2017-27. doi: 10.1523/JNEUROSCI.18-06-02017.1998.
3
Splice variant-specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments.N-甲基-D-天冬氨酸受体亚基NR1与神经元中间丝的剪接变体特异性相互作用。
J Neurosci. 1998 Jan 15;18(2):720-30. doi: 10.1523/JNEUROSCI.18-02-00720.1998.
4
Ion channel targeting in neurons.神经元中的离子通道靶向作用。
Bioessays. 1997 Oct;19(10):847-53. doi: 10.1002/bies.950191004.
5
Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain?肌肉特异性受体酪氨酸激酶(MuSK)的激酶结构域足以实现磷酸化,但不足以使乙酰胆碱受体聚集:MuSK胞外结构域的必需作用?
Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8848-53. doi: 10.1073/pnas.94.16.8848.
6
Interaction of ion channels and receptors with PDZ domain proteins.离子通道和受体与PDZ结构域蛋白的相互作用。
Curr Opin Neurobiol. 1997 Jun;7(3):368-73. doi: 10.1016/s0959-4388(97)80064-5.
7
PDZ domains: targeting signalling molecules to sub-membranous sites.PDZ结构域:将信号分子靶向至膜下位点
Bioessays. 1997 Jun;19(6):469-79. doi: 10.1002/bies.950190606.
8
Chick ciliary ganglion neurons contain transcripts coding for acetylcholine receptor-associated protein at synapses (rapsyn).鸡睫状神经节神经元在突触处含有编码乙酰胆碱受体相关蛋白(rapsyn)的转录本。
J Neurosci. 1997 Jul 1;17(13):5016-26. doi: 10.1523/JNEUROSCI.17-13-05016.1997.
9
Clustering of GABAA receptors by rapsyn/43kD protein in vitro.体外通过rapsyn/43kD蛋白对GABAA受体进行聚类。
Mol Cell Neurosci. 1997;8(6):430-8. doi: 10.1006/mcne.1997.0597.
10
Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold.Rapsyn是MuSK信号传导所必需的,并将突触成分募集到含有MuSK的支架上。
Neuron. 1997 Apr;18(4):623-35. doi: 10.1016/s0896-6273(00)80303-7.

To muster a cluster: anchoring neurotransmitter receptors at synapses.

作者信息

Colledge M, Froehner S C

机构信息

Department of Physiology, University of North Carolina, Chapel Hill, NC 27599-7545, USA.

出版信息

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3341-3. doi: 10.1073/pnas.95.7.3341.

DOI:10.1073/pnas.95.7.3341
PMID:9520364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC33847/
Abstract
摘要