Tinetti M E, Williams C S
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
J Gerontol A Biol Sci Med Sci. 1998 Mar;53(2):M112-9. doi: 10.1093/gerona/53a.2.m112.
Several preventive strategies have proven effective at reducing the occurrence and rate of falling. It remains to be determined, however, whether, and to what extent, falls and/or fall injuries are independent determinants of adverse functional outcomes in older persons.
A probability sample of 1,103 community-dwelling persons over age 71 years was followed for 3 years. The 957 cohort members (87%) who participated in at least one follow-up interview while residing in the community were included in this study. Outcome measures included one and three year change in basic and instrumental activities of daily living (BADLs-IADLs), social activities, and physical activities. Based on daily calendars and hospital surveillance, participants were placed into one of four levels of fall status: no falls, one fall without serious injury, at least two falls without serious injury, and one or more falls with serious injury. Hierarchical linear regression models, sequentially adding six domains of covariates, were constructed to examine fall status as a risk factor for change in function.
One noninjurious fall (beta = -.437; p < .01), at least two noninjurious falls (beta = -.877; p < .001); and at least one injurious fall (beta = -1.254; p < .001) were each associated with decline in BADL-IADL function over 3 years after adjusting for covariates (model R2 = .2617). Experiencing two or more noninjurious falls (beta = -.538; p < .05) was associated with decline in social activities (model R2 = .2779) while experiencing at least one injurious fall (beta = -.580; p < .01) was associated with decline in physical activity (model R2 = .4231).
Falls and fall injuries appear to be independent determinants of functional decline in community-dwelling older persons. Falling is a health condition meeting all criteria for prevention: high frequency, evidence of preventability, and high burden of morbidity.
多项预防策略已被证明在降低跌倒发生率方面有效。然而,跌倒和/或跌倒损伤是否以及在何种程度上是老年人不良功能结局的独立决定因素,仍有待确定。
对1103名71岁以上的社区居住者进行了为期3年的概率抽样随访。本研究纳入了957名队列成员(87%),他们在居住在社区期间至少参加了一次随访访谈。结局指标包括日常生活基本活动和工具性活动(BADLs-IADLs)、社交活动和身体活动在1年和3年的变化。根据每日日历和医院监测,参与者被分为四个跌倒状态级别之一:未跌倒、一次无重伤跌倒、至少两次无重伤跌倒以及一次或多次有重伤跌倒。构建分层线性回归模型,依次加入六个协变量域,以检验跌倒状态作为功能变化风险因素的情况。
在调整协变量后(模型R2 = 0.2617),一次无损伤跌倒(β = -0.437;p < 0.01)、至少两次无损伤跌倒(β = -0.877;p < 0.001)以及至少一次有损伤跌倒(β = -1.254;p < 0.001)均与3年内BADL-IADL功能下降相关。经历两次或更多次无损伤跌倒(β = -0.538;p < 0.05)与社交活动下降相关(模型R2 = 0.2779),而经历至少一次有损伤跌倒(β = -0.580;p < 0.01)与身体活动下降相关(模型R2 = 0.4231)。
跌倒和跌倒损伤似乎是社区居住老年人功能下降的独立决定因素。跌倒是一种符合所有预防标准的健康状况:高发生率、可预防性证据以及高发病负担。