Musil H E, Deutschmann W
Zentralbl Chir. 1976;101(6):330-8.
The application of antibiotics at the treatment of osteomyelitis resulted in a rise of the permanent successful treatment rate. This is especially true for the acute hematogenous osteomyelitis, to a certain extent also for the chronic exogenous one, at which even today the antibiotical therapy is not as important as a surgical intervention. Under consideration of the generally accepted therapeutical principles the special importance of a much individualized treatment adjusted to the clinical picture and disease stage is pointed out. The advantages and disadvantages of an application of antibiotics at the osteomyelitis are mentioned and we try to explain the reasons for occasional therapy failures. A special chapter is devoted to the methods of filling and sterilization of the osteomyelitis bone hollows. Our own experiences with an operative combination process are reported.
抗生素在骨髓炎治疗中的应用使永久成功治疗率有所提高。这在急性血源性骨髓炎中尤为明显，在一定程度上对于慢性外源性骨髓炎也是如此，即便在今天，抗生素治疗对于慢性外源性骨髓炎而言也不如手术干预重要。考虑到普遍认可的治疗原则，指出了根据临床症状和疾病阶段进行高度个体化治疗的特殊重要性。文中提到了在骨髓炎中应用抗生素的优缺点，并试图解释偶尔治疗失败的原因。有一个专门章节论述了骨髓炎骨腔填充和消毒的方法。报告了我们自己在手术联合治疗过程中的经验。
