Racine A D, Joyce T J, Li W, Chiasson M A
Department of Pediatrics, Albert Einstein College of Medicine, Jacobi Medical Center, Bronx, New York 10461, USA.
Pediatrics. 1998 Apr;101(4 Pt 1):682-8. doi: 10.1542/peds.101.4.682.
Although infant mortality rates have declined gradually in New York City for many years, the rate of that decline began to accelerate dramatically at the end of the 1980s.
To analyze the recent accelerated decline in infant mortality for three race/ethnicity designations in New York City and to investigate whether shifts in birth weight distribution or changes in birth weight-specific death rates were more important in determining these declines between 1988 to 1989 and 1992 to 1993.
Two complete cohorts of linked birth-death certificate files consisting of all live births in New York City in 1988 to 1989 and 1992 to 1993 were examined. For each cohort, separate multinomial logistic regressions were estimated by race/ethnicity to analyze the probability of a neonatal or postneonatal death relative to survival as a function of a spectrum of covariates. The coefficients from these regressions were used to construct direct and indirect standardization exercises to predict changes in infant mortality holding characteristics of the cohort, including birth weight distribution, constant over time, or holding the influence of determinants, including birth weight-specific death rates, constant over time.
For whites, Hispanics, and blacks, infant mortality rates declined by 27.4%, 24.8%, and 22.7%, respectively, between 1988 to 1989 and 1992 to 1993. For whites and blacks, the largest decreases occurred for neonatal mortality rates, whereas for Hispanics, postneonatal rates fell the greatest. Although infant mortality rates among very low birth weight infants (<1500 g) fell by 27.8%, 19.3%, and 16.6% for whites, Hispanics, and blacks, the greatest decreases in rates were seen among normal birth weight infants (>2500 g). Infant mortality rate declines for this category of infants reached 31%, 31.7%, and 31.3%, respectively, for whites, Hispanics, and blacks. Direct and indirect standardization exercises indicated that the most important factor in determining these declines were decreases in birth weight-specific death rates, not improvements in the birth weight distribution over time.
We conclude that the large decreases in infant mortality rates witnessed in New York City between 1988 to 1989 and 1992 to 1993 were attributable not to improvements in birth weight distribution of the population but to declines in birth weight-specific death rates and that normal birth weight infants showed the greatest improvement.
尽管纽约市的婴儿死亡率多年来一直在逐渐下降,但在20世纪80年代末,下降速度开始急剧加快。
分析纽约市三个种族/族裔群体近期婴儿死亡率的加速下降情况,并调查在1988年至1989年以及1992年至1993年期间,出生体重分布的变化或特定出生体重死亡率的变化在决定这些下降方面哪个更重要。
检查了两个完整的出生-死亡证明文件队列,包括1988年至1989年以及1992年至1993年纽约市的所有活产。对于每个队列,按种族/族裔分别进行多项逻辑回归,以分析新生儿或新生儿后期死亡相对于存活的概率,作为一系列协变量的函数。这些回归的系数用于构建直接和间接标准化分析,以预测婴儿死亡率的变化,保持队列特征(包括出生体重分布)随时间不变,或保持决定因素(包括特定出生体重死亡率)的影响随时间不变。
在1988年至1989年以及1992年至1993年期间,白人、西班牙裔和黑人的婴儿死亡率分别下降了27.4%、24.8%和22.7%。对于白人和黑人,最大降幅出现在新生儿死亡率方面,而对于西班牙裔,新生儿后期死亡率下降幅度最大。尽管极低出生体重婴儿(<1500克)中的白人、西班牙裔和黑人的婴儿死亡率分别下降了27.8%、19.3%和16.6%,但正常出生体重婴儿(>2500克)的死亡率下降幅度最大。此类婴儿的死亡率下降幅度在白人、西班牙裔和黑人中分别达到31%、31.7%和31.3%。直接和间接标准化分析表明,决定这些下降的最重要因素是特定出生体重死亡率的下降,而不是出生体重分布随时间的改善。
我们得出结论,1988年至1989年以及1992年至1993年期间纽约市婴儿死亡率的大幅下降并非归因于人口出生体重分布的改善,而是特定出生体重死亡率的下降,并且正常出生体重婴儿的改善最为显著。