Ferrando S, Goggin K, Sewell M, Evans S, Fishman B, Rabkin J
HIV Clinical Research Program, Cornell University Medical College, New York, New York, USA.
Am J Addict. 1998 Winter;7(1):51-60.
The authors conducted a longitudinal study of psychological adaptation to AIDS in subjects with and without lifetime and current substance use disorders (SUD), in a cohort of HIV+ gay/bisexual subjects. A sample of HIV+ gay/bisexual men (n = 183) and an HIV- comparison group (n = 84) were assessed for SUD, depression, and anxiety disorders. Among HIV+ men, combined lifetime (42%) but not current (11.5%) SUDs were more prevalent than in HIV- men (27% and 10%, respectively). HIV+ men with current SUD reported more depression, distress and diminished quality of life than HIV+ men with no SUD, but HIV-illness severity did not differ. HIV+ men in recovery did not differ from men with no lifetime history. Most HIV+ gay/bisexual men with SUD discontinue or reduce substance use before or subsequent to knowledge of their HIV infection, probably in an attempt to adopt a healthier lifestyle. However, for some HIV+ men, persistent substance abuse/dependence is accompanied by higher levels of distress and diminished quality of life, underscoring their need for treatment intervention.
作者对一组感染了HIV的男同性恋/双性恋者进行了一项纵向研究，以探讨有或无终生及当前物质使用障碍（SUD）的受试者对艾滋病的心理适应情况。对一组感染了HIV的男同性恋/双性恋男性（n = 183）和一个未感染HIV的对照组（n = 84）进行了物质使用障碍、抑郁症和焦虑症评估。在感染了HIV的男性中，终生合并物质使用障碍（42%）的患病率高于未感染HIV的男性（27%），但当前物质使用障碍（11.5%）的患病率与未感染HIV的男性（10%）相当。与没有物质使用障碍的感染了HIV的男性相比，当前存在物质使用障碍的感染了HIV的男性报告有更多的抑郁、痛苦和生活质量下降，但HIV疾病严重程度并无差异。已康复的感染了HIV的男性与无终生物质使用障碍病史的男性没有差异。大多数感染了HIV的有物质使用障碍的男同性恋/双性恋男性在知晓自己感染HIV之前或之后会停止或减少物质使用，这可能是为了尝试采用更健康的生活方式。然而，对于一些感染了HIV的男性来说，持续的物质滥用/依赖伴随着更高程度的痛苦和生活质量下降，这突出了他们对治疗干预的需求。
