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[肠道缺血的手术技术指南]

[Surgical technical guidelines in intestinal ischemia].

作者信息

Betzler M

机构信息

Klinik für Allgemeine Chirurgie, Unfallchirurgie und Gefässchirurgie, Alfried Krupp von Bohlen und Halbach Krankenhaus, Essen.

出版信息

Chirurg. 1998 Jan;69(1):1-7. doi: 10.1007/s001040050367.

DOI:10.1007/s001040050367
PMID:9522064
Abstract

Acute occlusive mesenteric ischemia is caused by a local impairment of splanchnic blood flow and poses a particular surgical challenge. Acute superior mesenteric occlusion is a medical/surgical emergency mandating prompt diagnosis (clinical awareness, angiography) and therapy (exploratory laparotomy with possible arterial reconstruction; embolectomy, thrombectomy; and/or bowel resection). The difficulty of early diagnosis is probably the most important cause of the high mortality which varies from 70% to 90% in arterial and functional mesenteric ischemia and from 20% to 70% in an acute thrombosis of the mesenteric veins. Improved survival from nonocclusive mesenteric ischemia is dependent upon the identification of high-risk groups and on aggressive diagnostic and therapeutic measures (intra-arterial infusion of papaverine through the angiographic catheter with or without bowel resection). For assessment of bowel viability, the clinical judgement during first- or second-look exploration is still the most reliable parameter. The surgical management of chronic mesenteric ischemia includes aortomesenteric grafting and transaortic endarterectomy in the majority of patients with comorbidity of cardiovascular arteriosclerotic diseases and results in a high rate of symptom-free patients. Prophylactic reconstruction of visceral arteries is indicated only in certain limited circumstances.

摘要

急性肠系膜缺血由内脏血流局部受损引起,构成了特殊的外科挑战。急性肠系膜上动脉闭塞是一种内科/外科急症,需要迅速诊断(临床警觉、血管造影)和治疗(可能需动脉重建的剖腹探查术;栓子切除术、血栓切除术;和/或肠切除术)。早期诊断困难可能是导致高死亡率的最重要原因,在动脉性和功能性肠系膜缺血中死亡率为70%至90%,在急性肠系膜静脉血栓形成中死亡率为20%至70%。非闭塞性肠系膜缺血患者生存率的提高取决于高危人群的识别以及积极的诊断和治疗措施(通过血管造影导管动脉内注入罂粟碱,可伴或不伴肠切除术)。对于评估肠存活能力,首次或再次探查时的临床判断仍是最可靠的参数。慢性肠系膜缺血的外科治疗包括在大多数合并心血管动脉硬化疾病的患者中行主动脉肠系膜血管移植术和经主动脉内膜切除术,术后无症状患者比例较高。仅在某些有限情况下才进行预防性内脏动脉重建。

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1
[Surgical technical guidelines in intestinal ischemia].[肠道缺血的手术技术指南]
Chirurg. 1998 Jan;69(1):1-7. doi: 10.1007/s001040050367.
2
[Surgical therapy of acute mesenteric ischemia].[急性肠系膜缺血的外科治疗]
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Dtsch Med Wochenschr. 2014 Jul;139(30):1540-4. doi: 10.1055/s-0034-1370157. Epub 2014 Jul 29.
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2
Intestinal ischemia: current treatment concepts.肠缺血:当前的治疗理念。
Langenbecks Arch Surg. 2011 Jan;396(1):3-11. doi: 10.1007/s00423-010-0726-y. Epub 2010 Nov 12.
3
Tissue oxygen saturation during colorectal surgery measured by near-infrared spectroscopy: pilot study to predict anastomotic complications.结直肠手术中通过近红外光谱法测量组织氧饱和度:预测吻合口并发症的初步研究
World J Surg. 2006 Mar;30(3):457-61. doi: 10.1007/s00268-005-0271-y.
4
Reperfusion injury after critical intestinal ischemia and its correction with perfluorochemical emulsion "perftoran".严重肠缺血后的再灌注损伤及其用全氟化合物乳剂“全氟托兰”进行的纠正。
World J Gastroenterol. 2005 Dec 7;11(45):7084-90. doi: 10.3748/wjg.v11.i45.7084.
5
[Nononcologic abdominal surgery in the elderly].[老年人的非肿瘤性腹部手术]
Chirurg. 2005 Jan;76(1):35-42. doi: 10.1007/s00104-004-0974-x.