Burguera Hernández J A, Arlandis Guzmán S, Sanz Chinesta S, Martínez Agulló E
Servicio de Neurología, Hospital Universitario La Fe., Valencia.
Neurologia. 1998 Jan;13(1):7-12.
Urinary and sexual symptoms in patients with multiple sclerosis (MS) are frequent, although this question has scarcely been addressed in our country. The aim of this study is to prospectively evaluate the presence of such symptoms in 77 MS patients. We have valued the neurological involvement and the degree of functional disability through the Minimum Dossier of Disability for Multiple Sclerosis. The urinary and sexual symptoms were collected through a directed survey. We have performed an urodynamic study in order to evaluate the bladder function. Urinary symptoms wire observed in 81.8% of patients, with predominance of the mixed syndrome (52%). Males show greater neurological affectation and functional disability, as well as greater urinary symptoms frequency (91%). The most frequent symptoms have been urgency (66.6%), frequency (60.3%) and dysuria (53.8%). The complications have been scarce, of infectious type (14.28%) and with female predominance. The most frequent urodynamic finding has been the detrusor hyperreflexia (60%). The minimum dossier of Disability for Multiple Sclerosis is useful to establish comparative parameters with other studies and with more specific urologic data. The presence of urinary symptoms in multiple sclerosis correlated with the degree of neurological (pyramidal and cerebellar) involvement and of functional disability in the Dysfunction Status Escale.
多发性硬化症(MS)患者的泌尿和性症状很常见,尽管在我国这个问题几乎没有得到过探讨。本研究的目的是前瞻性评估77例MS患者中此类症状的存在情况。我们通过多发性硬化症最小残疾档案评估了神经受累情况和功能残疾程度。通过定向调查收集泌尿和性症状。我们进行了尿动力学研究以评估膀胱功能。81.8%的患者出现泌尿症状,以混合综合征为主(52%)。男性表现出更严重的神经受累和功能残疾,以及更高的泌尿症状发生率(91%)。最常见的症状是尿急(66.6%)、尿频(60.3%)和排尿困难(53.8%)。并发症很少,为感染性类型(14.28%),女性居多。最常见的尿动力学表现是逼尿肌反射亢进(60%)。多发性硬化症最小残疾档案有助于建立与其他研究以及更具体的泌尿外科数据的比较参数。多发性硬化症中泌尿症状的存在与神经(锥体束和小脑)受累程度以及功能障碍状态量表中的功能残疾程度相关。