Macgregor I L, Knill J R, Meyer J H
Am J Dig Dis. 1976 Aug;21(8):641-4. doi: 10.1007/BF01071957.
The differing sensitivities of the gallbladder and pancreas to graded doses of CCK have been claimed as important in normal digestive events. As both secretin and CCK are thought to be released in response to normal feeding, we have reexamined the sensitivities of the gallbladder and pancreas to graded increases of CCK with a constant secretin background. Under such conditions the increase in output of pancreatic trypsin and bile salt occurred simultaneously, the dose-response curves being almost superimposable. Thus, under conditions more closely approaching normal postcibal events, the previously described differing sensitivities of the pancreas and gallbladder were not observed.
胆囊和胰腺对不同剂量胆囊收缩素（CCK）的敏感性差异，被认为在正常消化过程中很重要。由于促胰液素和胆囊收缩素都被认为是在正常进食时释放的，我们在促胰液素背景恒定的情况下，重新研究了胆囊和胰腺对递增剂量胆囊收缩素的敏感性。在这种情况下，胰蛋白酶和胆盐的分泌量同时增加，剂量反应曲线几乎完全重叠。因此，在更接近正常餐后情况的条件下，未观察到之前所描述的胰腺和胆囊敏感性差异。
