Han A M, Sleigh A, Vince J, Danaya R, Ogle G
Faculty of Medicine, University of Papua New Guinea, Port Moresby, Papua New Guinea.
P N G Med J. 1995 Dec;38(4):272-7.
A retrospective study of the records of children admitted to Port Moresby General Hospital with diarrhoea during 1992 and 1993 was carried out to determine the morbidity, mortality and risk factors associated with persistent diarrhoea. 858 admissions of children under five years of age who had diarrhoea were identified from the ward admission registers, and case records for 724 were studied. Persistent diarrhoea occurred in 20%, and nearly half of these were in the 12-23 months age group. Children with persistent diarrhoea had a case fatality rate of 4.9%. Seasonality was similar for both persistent and non-persistent diarrhoea. In the crude analysis children of 12 months and older had a greater risk of developing persistent diarrhoea than those less than 12 months (odds ratio for children 12-23 months was 2.0 and for children 24-59 months 1.7; confidence intervals were 1.2-3.1 and 1.0-2.9 respectively); however, this difference was not found after logistic regression analysis. Poor nutritional status was a significant risk factor for persistent diarrhoea and remained so after controlling for confounding variables (odds ratio 2.7; confidence interval 1.8-4.0).
对1992年和1993年期间莫尔斯比港总医院收治的腹泻儿童记录进行了一项回顾性研究，以确定与持续性腹泻相关的发病率、死亡率和风险因素。从病房入院登记册中识别出858名五岁以下腹泻儿童的入院情况，并对其中724例的病例记录进行了研究。持续性腹泻发生率为20%，其中近一半发生在12至23个月龄组。持续性腹泻儿童的病死率为4.9%。持续性腹泻和非持续性腹泻的季节性相似。在粗分析中，12个月及以上儿童发生持续性腹泻的风险高于12个月以下儿童（12至23个月儿童的比值比为2.0，24至59个月儿童为1.7；置信区间分别为1.2至3.1和1.0至2.9）；然而，在逻辑回归分析后未发现这种差异。营养状况差是持续性腹泻的一个重要风险因素，在控制混杂变量后仍然如此（比值比2.7；置信区间1.8至4.0）。
