Pearl G S
Department of Pathology, Orlando Regional Healthcare System, Florida, USA.
Clin Lab Med. 1998 Mar;18(1):39-64.
The neuropathology of trauma is reviewed based on the mechanism of injury. Pathology is divided into primary and secondary injury, based on the relationship to the time of injury. It is further divided by mechanism, with primary impact injury including skull fracture, epidural hematoma, brain contusion and laceration, and intracerebral hemorrhage; primary inertial injury including subdural hematoma, diffuse axonal injury, and diffuse vascular injury; and secondary injury including hypoxia/ischemia, brain swelling, infection, and increased intracranial pressure. The neuropathology of child abuse is also reviewed.
基于损伤机制对创伤的神经病理学进行了综述。根据与损伤时间的关系，病理学分为原发性损伤和继发性损伤。根据机制进一步细分，原发性冲击伤包括颅骨骨折、硬膜外血肿、脑挫伤和裂伤以及脑内出血；原发性惯性伤包括硬膜下血肿、弥漫性轴索损伤和弥漫性血管损伤；继发性损伤包括缺氧/缺血、脑肿胀、感染和颅内压升高。还对虐待儿童的神经病理学进行了综述。
