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梅克尔憩室的外科治疗。一项基于人群的流行病学研究。

Surgical management of Meckel's diverticulum. An epidemiologic, population-based study.

作者信息

Cullen J J, Kelly K A, Moir C R, Hodge D O, Zinsmeister A R, Melton L J

机构信息

Department of Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

Ann Surg. 1994 Oct;220(4):564-8; discussion 568-9. doi: 10.1097/00000658-199410000-00014.

Abstract

OBJECTIVE

The authors determined whether Meckel's diverticulum, discovered incidentally at operation, should be removed.

SUMMARY BACKGROUND DATA

It is not clear from the medical literature whether the risk of an incidental Meckel's diverticulectomy is greater than the risk of leaving the diverticulum in place.

METHODS

The authors used the medical experience of Olmsted County, Minnesota residents for the period 1950 to 1992 to answer the question.

RESULTS

During the period, 58 residents developed Meckel's complications that required diverticulectomies. The incidence of complications was 87 per 100,000 person-years, and the lifetime risk (to 80 years of age) of developing them was 6.4%. The risks were similar throughout the period and at all ages of life, but were greater among men (124 per 100,000 person-years) than women (50 per 100,000 person-years, p < 0.05). Diverticulectomies for complications carried an operative mortality and morbidity of 2% and 12% and a cumulative risk of long-term postoperative complications of 7%, whereas incidental diverticulectomies done in 87 residents during the period carried corresponding rates of only 1%, 2%, and 2%, respectively.

CONCLUSIONS

Meckel's diverticula discovered incidentally at operation should be removed for most patients, regardless of age.

摘要

目的

作者确定术中偶然发现的梅克尔憩室是否应予以切除。

总结背景数据

医学文献中尚不清楚偶然进行梅克尔憩室切除术的风险是否大于保留憩室的风险。

方法

作者利用明尼苏达州奥尔姆斯特德县居民1950年至1992年期间的医疗经验来回答这个问题。

结果

在此期间,58名居民出现了需要进行憩室切除术的梅克尔憩室并发症。并发症的发病率为每10万人年87例,至80岁时发生并发症的终生风险为6.4%。在整个期间以及生命的各个年龄段,风险相似,但男性(每10万人年124例)高于女性(每10万人年50例,p<0.05)。因并发症进行的憩室切除术的手术死亡率和发病率分别为2%和12%,术后长期并发症的累积风险为7%,而在此期间87名居民进行的偶然憩室切除术的相应发生率分别仅为1%、2%和2%。

结论

对于大多数患者,无论年龄大小,术中偶然发现的梅克尔憩室均应予以切除。

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