Yildirim A M, Güzel M Z, Yücel A, Aygit A C
Department of Plastic and Reconstructive Surgery, Cerrahpaşa Medical School, Istanbul University, Turkey.
J Reconstr Microsurg. 1998 Feb;14(2):117-20. doi: 10.1055/s-2007-1000153.
An experimental study in rats was designed to determine the effects of z-plasty on the patency of microvascular anastomosis. Eighty Sprague-Dawley rats of mixed sex were divided into two groups. In all animals, the left carotid arteries were used. In the first group (n = 40), a single z-plasty was done at the anterior side of the carotid artery before end-to-end anastomosis was performed. In the second group (n = 40), end-to-end anastomosis with interrupted sutures was done. Patency and the appearance of the anastomosis were evaluated 1 hr later, on the seventh postoperative day, and at the end of the third postoperative week. There was no vasospasm demonstrated in the first group. Patency rates were 100 percent for both groups after 1 hr. On the seventh postoperative day, one anastomosis in the first group (patency rate, 97.5 percent) and two anastomoses in the second group had failed (patency rate, 95 percent). Patency rates were similar at the third week. The difference was not statistically significant (p = 0.5). Histologic examinations demonstrated that z-plasty did not cause any adverse effects at the vessel wall or at the anastomosis.
设计了一项在大鼠身上进行的实验研究，以确定Z形整形术对微血管吻合通畅性的影响。80只混合性别的斯普拉格-道利大鼠被分为两组。在所有动物中，均使用左颈动脉。第一组（n = 40）在进行端端吻合前，在颈动脉前侧进行单次Z形整形术。第二组（n = 40）采用间断缝合进行端端吻合。在术后1小时、术后第7天和术后第三周结束时评估吻合口的通畅情况和外观。第一组未出现血管痉挛。两组术后1小时的通畅率均为100%。术后第7天，第一组有1例吻合失败（通畅率97.5%），第二组有2例吻合失败（通畅率95%）。第三周时通畅率相似。差异无统计学意义（p = 0.5）。组织学检查表明，Z形整形术未对血管壁或吻合口造成任何不良影响。
