Early stages in male germ cell differentiation in the mouse. Review article.
作者信息
Anderson R, Garcia-Castro M, Heasman J, Wylie C
机构信息
Department of Cell Biology and Neuroanatomy, University of Minnesota School of Medicine, Minneapolis 55455, USA.
出版信息
APMIS. 1998 Jan;106(1):127-32; discussion 132-3. doi: 10.1111/j.1699-0463.1998.tb01327.x.
Abstract
Primordial germ cells arise during gastrulation and migrate from the hindgut into the gonad primordium during early organogenesis. In this article, we discuss factors that control migration, proliferation and targeting of the PGCs. In particular we discuss how changes in adhesiveness control germ cell positioning in the gonad, and the molecules involved.
摘要
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