Furugaki K, Nagai E, Shinohara M, Saimura M, Ueki T, Toyoshima S, Kishikawa H
Department of Surgery, Kitakyushu City Wakamatsu Hospital, Kitakyushu, Japan.
Surg Today. 1998;28(2):219-22. doi: 10.1007/s005950050111.
We herein report a case of secretory carcinoma of the breast in a 73-year-old woman. Secretory carcinoma is an extremely rare tumor and demonstrates distinctive pathologic characteristics. This tumor frequently occurs in either children or adolescents, and thus has been called juvenile carcinoma. We encountered this rare tumor in an elderly woman. Aspiration biopsy cytology was performed twice, but the cytological diagnosis was not carcinoma. Such pathologic characteristics as mild atypia, the absence of hyperchromasia, and a minimal degree of pleomorphism in the tumor cells can thus lead to a cytological misdiagnosis. An excisional biopsy was performed and secretory carcinoma was finally diagnosed. Consequently, a modified radical mastectomy (Kodama's method) was performed 7 days later. We describe this very rare tumor's clinicopathologic characteristics.
我们在此报告一例73岁女性乳腺分泌性癌病例。分泌性癌是一种极其罕见的肿瘤，具有独特的病理特征。这种肿瘤常发生于儿童或青少年，因此被称为幼年性癌。我们在一名老年女性中遇到了这种罕见肿瘤。进行了两次细针穿刺活检细胞学检查，但细胞学诊断并非癌。肿瘤细胞的轻度异型性、无核染色质增深以及最小程度的多形性等病理特征可导致细胞学误诊。随后进行了切除活检，最终确诊为分泌性癌。因此，7天后进行了改良根治性乳房切除术（儿玉法）。我们描述了这种非常罕见肿瘤的临床病理特征。
