落叶型天疱疮。早期临床表现为疱疹样皮炎伴嗜酸性海绵形成。

Pemphigus foliaceus. Early clinical appearance as dermatitis herpetiformis with eosinophilic spongiosis.

作者信息

Osteen F B, Wheeler C E, Briggaman R A, Puritz E M

出版信息

Arch Dermatol. 1976 Aug;112(8):1148-52. doi: 10.1001/archderm.112.8.1148.

DOI:10.1001/archderm.112.8.1148

Abstract

We encountered an unusual case of pemphigus foliaceus in which there were early clinical signs of dermatitis herpetiformis with eosinophilic spongiosis histologically. Numerous authors have appreciated that eosinophilic spongiosis occurs in early pemphigus foliaceus, usually in the preacantholytic stage when the lesions may clinically simulate dermatitis herpetiformis. Recognition of eosinophilic spongiosis may help differentiate early pemphigus from other vesiculobullous disorders.

摘要

我们遇到了一例寻常型天疱疮的罕见病例，其组织学上有疱疹样皮炎的早期临床体征及嗜酸性海绵形成。许多作者已经认识到嗜酸性海绵形成见于早期寻常型天疱疮，通常在棘层松解前期，此时皮损在临床上可能类似疱疹样皮炎。认识嗜酸性海绵形成可能有助于早期天疱疮与其他水疱大疱性疾病相鉴别。