落叶型天疱疮早期的嗜酸性海绵形成
Eosinophilic spongiosis in early pemphigus foliaceus.
作者信息
Brodersen I, Frentz G, Thomsen K
出版信息
Acta Derm Venereol. 1978;58(4):368-9.
PMID:82338
Abstract
A case of widespread non-specific, itchy exanthema in a 74-year-old female is presented. An early skin biopsy showed eosinophilic spongiosis. Later a dermatitis herpetiformis-like eruption developed. However, immunofluorescence microscopy showed intercellular IgG deposits characteristic of pemphigus. Recognition of eosinophilis spongiosis may be helpful in differentiating early pemphigus from other bullous diseases.
摘要
本文报告了一例74岁女性广泛分布的非特异性瘙痒性皮疹病例。早期皮肤活检显示嗜酸性海绵形成。后来出现了疱疹样皮炎样皮疹。然而，免疫荧光显微镜检查显示了天疱疮特有的细胞间IgG沉积。认识到嗜酸性海绵形成可能有助于早期天疱疮与其他大疱性疾病的鉴别。
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