Naarding P, van den Broek W W, Koudstaal P J
Psychiatrisch Ziekenhuis Amsterdam.
Tijdschr Gerontol Geriatr. 1997 Dec;28(6):254-9.
In this article the authors describe two different ways in which the relationship between affective disorders and cerebrovascular disease can be studied. First, the occurrence of so called 'post stroke depression' offers an opportunity to study this relationship. Second, neuroradiological investigations in patients with a major depressive disorder can be performed. The authors review the literature on both subjects. Until now, unequivocal conclusions concerning vascular lesions on CT or MRI and depressive features in the elderly cannot be drawn from research data available. Moreover, the so-called Post-stroke depression is still not fully understood. Some difficulties encountered in this area of research are also addressed. The authors suggest a neurological cause for the late onset types of major depressive illness and also suggest that these depressions are phenomenologically different from the early onset subtypes of depressive illness. The post stroke depression also seems to differ phenomenologically from major depression according to DSM-criteria.
在本文中，作者描述了研究情感障碍与脑血管疾病之间关系的两种不同方法。第一，所谓的“中风后抑郁”的发生为研究这种关系提供了一个机会。第二，可以对重度抑郁症患者进行神经放射学检查。作者回顾了关于这两个主题的文献。到目前为止，从现有的研究数据中还无法得出关于老年人CT或MRI上的血管病变与抑郁特征的确切结论。此外，所谓的中风后抑郁仍未被完全理解。本文还讨论了该研究领域中遇到的一些困难。作者提出了重度抑郁症晚发型的神经学病因，并指出这些抑郁症在现象学上与抑郁症早发型亚型不同。根据《精神疾病诊断与统计手册》标准，中风后抑郁在现象学上似乎也与重度抑郁症不同。
