Aarnink R G, de la Rosette J J, Witjes J A, Debruyne F M, Wijkstra H
Afdeling Urologie Academisch Ziekenhuis Nijmegen.
Tijdschr Gerontol Geriatr. 1997 Dec;28(6):264-71.
This paper presents the current diagnostics of patients with prostate related problems (lower urinary tract symptoms) who visit the urology clinic. The diagnostic triad for prostate cancer detection is presented, consisting of a serum Prostate-Specific Antigen test, a digital rectal examination to palpate the prostate, and transrectal ultrasound of the prostate to visualise internal structures and guide the urologist in taking biopsies. The results of the tests for a biopsied population of 232 patients illustrate the shortcomings of the individual tests in predicting the presence of a malignancy. Biopsies are needed to prove or rule out prostate cancer in case of a suspicion. Future developments in early detection of prostate cancer are directed to improve the clinical use of the current diagnostic triad, and to identify new diagnostic tools.
本文介绍了前往泌尿外科诊所就诊的前列腺相关问题（下尿路症状）患者的当前诊断情况。文中呈现了用于前列腺癌检测的诊断三联法，包括血清前列腺特异性抗原检测、用于触诊前列腺的直肠指检，以及用于观察内部结构并指导泌尿科医生进行活检的经直肠前列腺超声检查。对232例接受活检患者的检测结果表明了各项单独检测在预测恶性肿瘤存在方面的不足。如有怀疑，需要进行活检以证实或排除前列腺癌。前列腺癌早期检测的未来发展方向是改善当前诊断三联法的临床应用，并识别新的诊断工具。
