乳腺肿瘤细胞组分抑制白细胞迁移的机制。
Mechanisms of leucocyte migration inhibition by breast tumour cell fractions.
作者信息
Jones B M
出版信息
Br J Cancer. 1976 Jul;34(1):14-9. doi: 10.1038/bjc.1976.115.
Abstract
Leucocyte migration inhibition by autologous breast tumour cell fractions was mediated by a soluble factor synthesized and released by mononuclear leucocytes and active against migrating granulocytes. This mechanism is similar to that previously described in respect to cell-mediated sensitivity to microbial antigens. Alternative mechanisms involving directly reactive granulocytes or cytophilic antibodies were rarely operative in the migration tests.
摘要
自体乳腺肿瘤细胞组分对白细胞迁移的抑制作用是由单核白细胞合成并释放的一种可溶性因子介导的，该因子对迁移的粒细胞具有活性。这一机制与先前描述的细胞介导的对微生物抗原的敏感性机制相似。在迁移试验中，涉及直接反应性粒细胞或嗜细胞抗体的其他机制很少起作用。
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本文引用的文献
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Passive sensitization of tissue cells. II. Ability of cytophilic antibody to render the migration of guinea pig peritoneal exudate cells inhibitable by antigen.组织细胞的被动致敏作用。II. 嗜细胞性抗体使豚鼠腹腔渗出细胞的迁移被抗原抑制的能力。
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