Mathoulin-Pélissier S, Vicariot M, Gross S, Waller C, Courtois F, Eghbali H, Saves M, Verret C, Salmi L R
Centre national d'hémovigilance, Bordeaux.
Transfus Clin Biol. 1997 Dec;4(6):533-40. doi: 10.1016/s1246-7820(97)80078-x.
The aim of this study was to describe blood recipients and blood components transfused during the first 24 hours in 13 French hospitals. We included all blood recipients who had not had any blood transfusion within the past six months. Recipients were screened for red cell alloantibodies, the alanine aminotransferase activity and specific viral markers (hepatitis B and C, Human Immunodeficiency Virus). Eligible patients represented 47% of the all transfused. Among the 371 patients included, 57% were males and 71% were transfused in a surgical unit. Alloantibodies, non specific and specific viral markers were detected in 3%, 19% and 2% respectively. Among the patients included, 42 received 172 autologous units. In total, 1056 allogeneic units (an average of 3 units per patient) were transfused; blood products were leucocyte-depleted (49%) or leucocyte-poor (20%); 54% of red cell units were matched for antigens Rh and Kell. Neoplasms were the most frequently reported disease for which patients were transfused. This study provides baseline blood transfusion information on recipients and blood utilization for a specific period in French hospitals. Following this study, a national study will allow the clarification of the characteristics, for instance the surgical procedures requiring transfusion.
本研究旨在描述法国13家医院在最初24小时内的输血受者及所输注的血液成分。我们纳入了过去六个月内未接受过任何输血的所有输血受者。对受者进行红细胞同种抗体、丙氨酸转氨酶活性及特定病毒标志物（乙型和丙型肝炎、人类免疫缺陷病毒）筛查。符合条件的患者占所有输血患者的47%。在纳入的371例患者中，57%为男性，71%在外科病房接受输血。分别有3%、19%和2%的患者检测到同种抗体、非特异性和特异性病毒标志物。纳入的患者中，42例接受了172单位自体血。总共输注了1056单位异体血（平均每位患者3单位）；血液制品进行了白细胞去除处理（49%）或白细胞含量低（20%）；54%的红细胞单位进行了Rh和Kell抗原配型。肿瘤是报告的患者接受输血最常见的疾病。本研究提供了法国医院特定时期内输血受者及血液利用情况的基线输血信息。在这项研究之后，一项全国性研究将有助于明确相关特征，例如需要输血的外科手术。
