Spraul C W, Grossniklaus H E, Lang G K
L. F. Montgomery Eye Pathology Laboratory, Emory University School of Medicine Atlanta, GA, USA.
Klin Monbl Augenheilkd. 1997 Nov;211(5):342-4. doi: 10.1055/s-2008-1035145.
A 62-year-old woman was evaluated for a bilateral subconjunctival mass that had been present for 6 months. With magnetic resonance imaging the lesion could not be delineated form the lacrimal glands. A biopsy was performed and histologic examination exhibited a xanthogranulomatous lesion with multiple giant-cells of the Touton type. The differential diagnosis of the adult xanthogranuloma is Erdheim-Chester disease, necrobiotic granuloma, xanthoma, Langerhans histiocytosis, and Rosai-Dorfman syndrome.
Hyperlipemia should be excluded, in addition, in the presence of necrobiosis, paraproteinemia.
一名62岁女性因双侧结膜下肿物就诊,该肿物已存在6个月。磁共振成像无法将该病变与泪腺区分开来。进行了活检,组织学检查显示为伴有多个图顿型巨细胞的黄色肉芽肿性病变。成人黄色肉芽肿的鉴别诊断包括厄尔德海姆-切斯特病、渐进性坏死性肉芽肿、黄瘤、朗格汉斯细胞组织细胞增多症和罗萨伊-多夫曼综合征。
除存在渐进性坏死、副蛋白血症外,还应排除高脂血症。