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[眼部带状疱疹继发霍纳综合征]

[Horner's syndrome secondary to ophthalmic herpes zoster].

作者信息

Tola-Arribas M A, Zarco-Tejada J M, Marco-Llorente J

机构信息

Servicio de Neurología, Hospital Universitario, Valladolid, España.

出版信息

Rev Neurol. 1997 Dec;25(148):1922-4.

PMID:9528032
Abstract

INTRODUCTION

Ophthalmoparesias is a frequent complication of ophthalmic herpes zoster. It occurs in 31% of all cases. However, the presence of Horner's syndrome during viral reactivation is a rarity which has only been previously described on two occasions, and never associated with cranial nerve involvement.

CLINICAL CASE

We describe a patient with the first case of Horner's syndrome secondary to ophthalmic herpes zoster, with simultaneous, homolateral lesions of the third and sixth cranial nerves. Clinical evaluation, the course of the disorder, negative magnetic resonance studies and tests with cocaine and foledrin eye drops confirmed the presence of a post-ganglionar sympathetic lesion, probably situated in the ipsilateral cavernous sinus.

CONCLUSIONS

Ophthalmoparesias as a complication of ophthalmic herpes zoster may have various origins. Diffusion of viral particles from the Gasserian ganglion and branches of the trigeminal nerve to adjacent structures, muscles, nerves and vessels, is the mechanism often mentioned. Presence of a simultaneous sympathetic lesion is very rare and of unknown pathology. However, it is probable that the origin of the lesion of the vegetative fibres is the same as that of the sensory or motor fibres, and adjacent inflammatory process caused by the virus extending. We analyze the factors involved in the low incidence of this association.

摘要

引言

眼肌麻痹是眼部带状疱疹的常见并发症,在所有病例中的发生率为31%。然而,病毒再激活期间出现霍纳综合征的情况较为罕见,此前仅有两次相关描述,且从未与脑神经受累相关。

临床病例

我们描述了一例继发于眼部带状疱疹的霍纳综合征患者,同时伴有同侧第三和第六脑神经损伤。临床评估、疾病进程、磁共振检查结果阴性以及使用可卡因和福里德林眼药水进行的测试证实了节后交感神经损伤的存在,损伤可能位于同侧海绵窦。

结论

作为眼部带状疱疹并发症的眼肌麻痹可能有多种起源。病毒颗粒从半月神经节和三叉神经分支扩散到相邻结构、肌肉、神经和血管是常被提及的机制。同时存在交感神经损伤的情况非常罕见,其病理原因不明。然而,自主神经纤维损伤的起源可能与感觉或运动纤维相同,是由病毒扩散引起的相邻炎症过程所致。我们分析了这种关联发生率较低的相关因素。

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