Kinney E L, Allen R P, Weidner W A, Pierce W S, Leaman D M, Zelis R F
Pacing Clin Electrophysiol. 1979 Mar;2(2):196-202. doi: 10.1111/j.1540-8159.1979.tb05201.x.
This report describes the management of a woman with multiple pulmonary emboli secondary to a large right atrial clot which had formed around her permanent transvenous pacemaker. She continued to have pulmonary emboli despite adequate anticoagulation. Removal of the catheter and pacing required right atriotomy under cover of cardiopulmonary bypass. Additionally, eight English language case reports of symptomatic pericatheter thromboses are reviewed. In these cases, pericatheter clot resulted either in right-sided inlet obstruction or pulmonary emboli. The mortality rate was 75%. Although the cause for our patent's thromboembolic events is uncertain, congestive heart failure was a predisposing factor in 75% of the other reported cases. We suggest that pacemaker patients in congestive heart failure might benefit greatly from chronic anticoagulation.
本报告描述了一名女性患者的治疗情况,该患者因围绕其永久性经静脉起搏器形成的巨大右心房血栓继发多发性肺栓塞。尽管进行了充分的抗凝治疗,她仍持续发生肺栓塞。在体外循环支持下,通过右心房切开术取出导管并进行起搏。此外,还回顾了8例有症状的导管周围血栓形成的英文病例报告。在这些病例中,导管周围血栓导致右侧入口梗阻或肺栓塞。死亡率为75%。虽然我们这位患者血栓栓塞事件的原因尚不确定,但在其他报告病例中,75%的患者存在充血性心力衰竭这一诱发因素。我们建议,充血性心力衰竭的起搏器患者可能会从长期抗凝治疗中大大获益。