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[宫颈癌和子宫内膜癌的流行病学]

[Epidemiology of cervical and endometrial cancer].

作者信息

Schaffer P

机构信息

Laboratoire d'Epidémiologie et de Santé Publique, Faculté de Médecine, Strasbourg.

出版信息

Bull Acad Natl Med. 1997 Oct;181(7):1347-62; discussion 1363-4.

PMID:9528181
Abstract

In 1995, in France, the estimation of the cervix cancer incidence, with 3,300 new cases, is of 10.3 per 100,000, and the incidence of the endometrial cancer with 3,268 new cases, is of 13.8 per 100,000. The decrease of the incidence of the cervical cancer is of more than 50%, in 1975, the incidence was of 22.4 per 100,000. For the endometrial cancer, the decrease is insignificant, as in 1975, the incidence was of 14.4 per 100,000. This phenomenon has been observed in most european countries. The incidence of the adenocarcinoma of the cervix remains stable. The relative survival at 5 years, at all ages in the French cancer registry of Bas-Rhin is of 65% for the cervical cancer and of 73% for the corpus uteri cancer. However, no improvement has been observed since 1975. The risk factors are quite well-known concerning the cervical cancer, there is a strong correlation with the sexual activities, age at first intercourse, the multiplicity of the partners, which clearly shows that the cervical cancer is a sexually transmitted disease. Concerning the endometrial cancer, the risk factors are mostly linked with the reproductive life: age at menarche, parity, age at first birth, menstrual irregularities, infertility and menopause.

摘要

1995年,在法国,宫颈癌的发病率估计为每10万人中有3300例新发病例,即10.3例;子宫内膜癌的发病率为每10万人中有3268例新发病例,即13.8例。宫颈癌发病率下降超过50%,1975年其发病率为每10万人中有22.4例。对于子宫内膜癌,发病率下降不显著,1975年其发病率为每10万人中有14.4例。这种现象在大多数欧洲国家都有观察到。宫颈腺癌的发病率保持稳定。在法国下莱茵省癌症登记处,所有年龄段宫颈癌的5年相对生存率为65%,子宫体癌为73%。然而,自1975年以来未观察到改善情况。关于宫颈癌,其危险因素已广为人知,它与性行为、初次性交年龄、性伴侣数量密切相关,这清楚地表明宫颈癌是一种性传播疾病。关于子宫内膜癌,危险因素大多与生殖生活有关:初潮年龄、产次、初育年龄、月经不规律、不孕和绝经。

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