Fabiani L, Onori L
Dipartimento di Medicina interna e Sanità pubblica, Università degli studi dell'Aquila.
Clin Ter. 1997 Dec;148(12):609-16.
The Authors have appraised, in a group of 20 patients suffering from "non-ulcer, non-reflux dyspepsia", the therapeutical action and tolerance of the oligomineral Santa Croce water from the Sponga spring administered at a dose of 500 mL with the main meals up to an overall quantity of 1.5 L per day for ten days. When compared with a comparable control group, taking fairly mineralized water of known composition and free of contaminants, the group of patients treated showed a significant reduction both in the number and intensity of the symptoms marking the dyspeptic condition including above all pyrosis and sensation of epigastric heaviness and laborious digestion. As a first hypothesis, the hydropinic treatment might have indirectly favoured post-prandial gastric emptying, through an action of reduction of endogastric osmolarity and pH. The only collateral effect, reported by only five subjects, consisted of an annoying pollakiuria and nycturia.
作者对一组20名患有“非溃疡性、非反流性消化不良”的患者进行了评估，让他们服用来自斯蓬加泉的低矿物质圣十字水，剂量为每餐500毫升，每天总量达1.5升，持续十天，观察其治疗作用和耐受性。与服用成分已知且无污染的相当矿化水的可比对照组相比，接受治疗的患者组在标志着消化不良状况的症状数量和强度方面均有显著降低，尤其是烧心、上腹部沉重感和消化困难等症状。作为第一个假设，水疗可能通过降低胃内渗透压和pH值的作用，间接地促进了餐后胃排空。唯一的副作用（仅5名受试者报告）是烦人的尿频和夜尿症。
