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城市青少年药物滥用模式的变化

The changing pattern of substance abuse in urban adolescents.

作者信息

Brasseux C, D'Angelo L J, Guagliardo M, Hicks J

机构信息

Children's National Medical Center, Children's Research Institute, Center VI, Washington, DC, USA.

出版信息

Arch Pediatr Adolesc Med. 1998 Mar;152(3):234-7. doi: 10.1001/archpedi.152.3.234.

Abstract

OBJECTIVES

To determine the prevalence of specific drug use in adolescents attending an adolescent health clinic and to compare current rates with a similar previous study.

DESIGN

Blinded and anonymous urine samples obtained from patients presenting for routine health care were tested for the presence of cannabinoids, phencyclidine (PCP), amphetamines, opiates, and cocaine.

SETTING

Adolescent medicine outpatient clinic.

PATIENTS

Patients were between 12 and 21 years of age. Specimens from 1313 patients in 1995 to 1996 and 1312 patients in 1989 to 1990 were tested.

MAIN OUTCOME MEASURES

Current drug use rates were compared with a similar screening of patients conducted in 1989 to 1990. Comparisons between studies were made on the basis of specific drug, age, and sex.

RESULTS

For the most recent patient group, 14% were positive for 1 or more drugs and 13% were positive for cannabinoids. Males were significantly more likely to test positive for drug use than females. The oldest adolescents were more likely to test positive for drug use than younger adolescents. Comparing the 2 study year cohorts, patients tested recently were significantly more likely to have urine tests positive for at least 1 drug and cannabinoids in particular and less likely to have urine tests positive for cocaine.

CONCLUSIONS

There has been an increase in positive urine tests in patients seen in our ambulatory clinic, with a strong shift toward cannabinoids and a shift away from cocaine. Practitioners need to be aware that drug use patterns in adolescents can shift relatively abruptly and counseling should be targeted to current drug use patterns.

摘要

目的

确定在青少年健康诊所就诊的青少年中特定药物的使用流行率,并将当前比率与之前的一项类似研究进行比较。

设计

从前来接受常规医疗保健的患者中获取的盲法和匿名尿液样本,检测其中是否存在大麻素、苯环己哌啶(PCP)、苯丙胺、阿片类药物和可卡因。

地点

青少年医学门诊诊所。

患者

患者年龄在12至21岁之间。对1995年至1996年的1313名患者以及1989年至1990年的1312名患者的样本进行了检测。

主要观察指标

将当前药物使用率与1989年至1990年对患者进行的类似筛查结果进行比较。根据特定药物、年龄和性别对研究进行比较。

结果

对于最近的患者组,14%的患者一种或多种药物检测呈阳性,13%的患者大麻素检测呈阳性。男性药物使用检测呈阳性的可能性显著高于女性。年龄最大的青少年药物使用检测呈阳性的可能性高于年龄较小的青少年。比较这两个研究年份的队列,最近接受检测的患者尿液中至少有一种药物检测呈阳性的可能性显著更高,尤其是大麻素,而尿液中可卡因检测呈阳性的可能性更低。

结论

在我们的门诊诊所就诊的患者中,尿液检测呈阳性的情况有所增加,用药模式明显向大麻素转变,远离可卡因。从业者需要意识到青少年的药物使用模式可能相对突然地发生变化,咨询应针对当前的药物使用模式。

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