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正电子发射断层扫描(PET)衍生的丘脑葡萄糖代谢测量值与脑电图(EEG)α波功率之间的关系。

Relations between PET-derived measures of thalamic glucose metabolism and EEG alpha power.

作者信息

Larson C L, Davidson R J, Abercrombie H C, Ward R T, Schaefer S M, Jackson D C, Holden J E, Perlman S B

机构信息

Department of Psychology, University of Wisconsin, Madison 53706, USA.

出版信息

Psychophysiology. 1998 Mar;35(2):162-9.

PMID:9529942
Abstract

Electroencephalogram (EEG) alpha power has been demonstrated to be inversely related to mental activity and has subsequently been used as an indirect measure of brain activation. The thalamus has been proposed as an important site for modulation of rhythmic alpha activity. Studies in animals have suggested that cortical alpha rhythms are correlated with alpha rhythms in the thalamus. However, little empirical evidence exists for this relation in humans. In the current study, resting EEG and a fluorodeoxyglucose positron emission tomography scan were measured during the same experimental session. Over a 30-min period, average EEG alpha power across 28 electrodes from 27 participants was robustly inversely correlated with glucose metabolic activity in the thalamus. These data provide the first evidence for a relation between alpha EEG power and thalamic activity in humans.

摘要

脑电图(EEG)的阿尔法波功率已被证明与精神活动呈负相关,随后被用作大脑激活的间接测量指标。丘脑被认为是调节节律性阿尔法活动的重要部位。动物研究表明,皮层阿尔法节律与丘脑中的阿尔法节律相关。然而,在人类中,这种关系的实证证据很少。在本研究中,在同一实验过程中测量了静息脑电图和氟脱氧葡萄糖正电子发射断层扫描。在30分钟的时间段内,27名参与者的28个电极上的平均脑电图阿尔法波功率与丘脑中的葡萄糖代谢活动呈显著负相关。这些数据首次为人类脑电图阿尔法波功率与丘脑活动之间的关系提供了证据。

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