在静息状态和体育锻炼期间用磁共振成像测量主动脉和肺循环血流量。
Measurement of aortic and pulmonary flow with MRI at rest and during physical exercise.
作者信息
Niezen R A, Doornbos J, van der Wall E E, de Roos A
机构信息
Department of Radiology, Leiden University Medical Centre, The Netherlands.
出版信息
J Comput Assist Tomogr. 1998 Mar-Apr;22(2):194-201. doi: 10.1097/00004728-199803000-00006.
PURPOSE
Our aim was to assess the feasibility of measuring great vessel flow during submaximal exercise using MR flow mapping.
METHOD
In 16 healthy volunteers, MR measurements of great vessel flow were obtained at rest and during two levels of submaximal physical exercise using an MR-compatible bicycle ergometer.
RESULTS
Great vessel flow showed good correlation at rest and during exercise (r = 0.9, p < 0.0005). Significant increase in heart rate was observed during exercise. Aortic flow volume increased from 64 +/- 13 ml/beat at rest to 71 +/- 11 ml/beat at 50 W (p < 0.0005) to 79 +/- 13 ml/beat at 100 W (p < 0.0005). Pulmonary flow volume increased from 63 +/- 14 ml/beat at rest to 70 +/- 13 ml/beat at 50 W (p < 0.005) to 76 +/- 12 ml/beat at 100 W (p = NS).
CONCLUSION
Quantification of great vessel flow can be performed safely in healthy volunteers using MR flow measurements during submaximal physical exercise. These measurements may be used to study hemodynamic abnormalities in patients with cardiac disease.
目的
我们的目的是评估在次最大运动量运动期间使用磁共振血流成像测量大血管血流的可行性。
方法
对16名健康志愿者，使用与磁共振兼容的自行车测力计，在静息状态及两个次最大运动量水平的运动期间进行大血管血流的磁共振测量。
结果
大血管血流在静息状态和运动期间显示出良好的相关性（r = 0.9，p < 0.0005）。运动期间观察到心率显著增加。主动脉血流量从静息时的64±13毫升/搏增加到50瓦时的71±11毫升/搏（p < 0.0005），再到100瓦时的79±13毫升/搏（p < 0.0005）。肺血流量从静息时的63±14毫升/搏增加到50瓦时的70±13毫升/搏（p < 0.005），再到100瓦时的76±12毫升/搏（p =无统计学意义）。
结论
在健康志愿者中，使用次最大运动量运动期间的磁共振血流测量可以安全地进行大血管血流的量化。这些测量可用于研究心脏病患者的血流动力学异常。
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