Arad Y, Spadaro L A, Roth M, Scordo J, Goodman K, Sherman S, Lledo A, Lerner G, Guerci A D
Department of Preventive Cardiology, St. Francis Hospital, Roslyn, NY 11576, USA.
J Comput Assist Tomogr. 1998 Mar-Apr;22(2):207-11. doi: 10.1097/00004728-199803000-00008.
Electron beam CT (EBCT)-derived coronary artery calcium scores correlate with the extent of atherosclerosis, but there is a substantial variance about the general relationship between coronary calcification and coronary atherosclerosis. The relationship between calcification and atherosclerosis may also differ in various arteries. This study was designed to evaluate whether the relation between carotid artery intima-media thickness (IMT) and carotid artery calcium could be used as a correction factor to improve the correlation between coronary calcification and coronary atherosclerosis.
We measured atherosclerosis in the coronary and carotid arteries by angiography and ultrasonography, respectively, and quantified coronary and carotid calcium deposition with EBCT in 50 subjects. The correlation between the findings in the carotid and coronary arteries was investigated.
Coronary artery calcium score correlated with coronary angiography and with carotid calcium score. Coronary stenosis correlated with carotid IMT. There was no meaningful correlation of carotid IMT and carotid calcium.
There is an intraindividual variation in the relationship of plaque mass to calcification among different vessels. The relation between carotid artery calcification and carotid IMT is not predictive of the relation between coronary artery calcification and coronary obstruction.
电子束CT（EBCT）得出的冠状动脉钙化积分与动脉粥样硬化程度相关，但冠状动脉钙化与冠状动脉粥样硬化之间的总体关系存在很大差异。钙化与动脉粥样硬化之间的关系在不同动脉中也可能不同。本研究旨在评估颈动脉内膜中层厚度（IMT）与颈动脉钙化之间的关系是否可作为校正因子，以改善冠状动脉钙化与冠状动脉粥样硬化之间的相关性。
我们分别通过血管造影和超声检查测量了50名受试者冠状动脉和颈动脉的动脉粥样硬化情况，并用EBCT对冠状动脉和颈动脉的钙沉积进行了量化。研究了颈动脉和冠状动脉检查结果之间的相关性。
冠状动脉钙化积分与冠状动脉造影以及颈动脉钙化积分相关。冠状动脉狭窄与颈动脉IMT相关。颈动脉IMT与颈动脉钙化之间无显著相关性。
不同血管中斑块质量与钙化之间的关系存在个体内差异。颈动脉钙化与颈动脉IMT之间的关系不能预测冠状动脉钙化与冠状动脉阻塞之间的关系。
