Lemke M R, Broderick A, Hartmann W
Klinik für Psychiatrie und Psychotherapie, Christian-Albrechts-Universität zu Kiel.
Fortschr Neurol Psychiatr. 1998 Jan;66(1):43-8. doi: 10.1055/s-2007-995238.
Intensity of symptoms including mood and psychomotor activity has been shown to vary according to the time of the day in a group of depressed patients. This pattern represents one diagnostic criterion for the melancholic type of depression. The variation of intensity is experienced by the patient and can be observed as a behavioral symptom. However, the relation of circadian alterations in psychomotor activity and depressed mood remains unclear. Therefore, spontaneous motor activity and experienced intensity of symptoms were measured in 21 depressed patients who showed daily variations of subjective symptoms. Patients felt significantly less active, awake, and more depressed in the morning compared to the evening. However, corresponding activity levels, which were measured by actigraphy, appeared significantly higher in the morning compared to the evening. Increased motor activity could represent the observable behavioral equivalent of self-experienced psychomotor retardation and depressed mood.