Legraverend M, Michelot R
Biochimie. 1976;58(6):723-9. doi: 10.1016/s0300-9084(76)80397-5.
With the aim of studying analogues of S adenosyl homocysteine and S adenosyl methionine as potential inhibitors of methyl-transferases, we describe the syntheses of such analogues, in which either the amino-acid chain is replaced by various aliphatic radicals of the N 6 amino group of adenine is substituted.
为了研究S-腺苷高半胱氨酸和S-腺苷甲硫氨酸的类似物作为甲基转移酶的潜在抑制剂,我们描述了此类类似物的合成方法,其中腺嘌呤的N6氨基的氨基酸链被各种脂肪族基团取代,或者腺嘌呤的N6氨基被取代。