de Gourville E M, Mabey D, Quigley M, Jack N, Mahabir B
The Caribbean Epidemiology Centre, Trinidad and Tobago, West Indies.
Int J STD AIDS. 1998 Mar;9(3):151-7. doi: 10.1258/0956462981921918.
Risk factors for HIV infection in partners of HIV-seropositive index cases were investigated in a cross-sectional survey. Between September 1992 and April 1994 a total of 251 HIV-infected persons and 76 of their sexual partners were interviewed at the main sexually transmitted diseases (STDs) clinic in Trinidad. All participants gave signed consent and responded to a questionnaire. Sixty-four couples had risks for HIV infection through heterosexual intercourse only. However, many recruited sex partners (57/64) reported heterosexual intercourse with persons in addition to the index cases. Overall HIV concordance (both index case and partner HIV infected) was 45% in the couples. HIV concordance was not found to be related to the sexual practices within the studied unions nor to the clinical status of the index case. After allowing for confounding factors there was an increased risk for HIV concordance in couples in unions for > or = 1 year (adjusted OR 3.48; 95% CI 0.89-13.69, P = 0.055), and in those in which sex partners had a past history of genital sores (adjusted for prostitution: OR 4.50; 95% CI 1.01-20.4). Interventions targeted at reducing high-risk sexual behaviour, prostitution and cocaine use could be beneficial in reducing the spread of STDs and HIV in Trinidad.
在一项横断面调查中，对HIV血清反应阳性的索引病例的性伴侣感染HIV的危险因素进行了调查。1992年9月至1994年4月期间，在特立尼达的主要性传播疾病（STD）诊所，共对251名HIV感染者及其76名性伴侣进行了访谈。所有参与者均签署了知情同意书并回答了一份问卷。64对伴侣仅通过异性性行为有感染HIV的风险。然而，许多招募的性伴侣（57/64）报告除了索引病例外还与其他人有异性性行为。在这些伴侣中，总体HIV一致性（索引病例和伴侣均感染HIV）为45%。未发现HIV一致性与所研究伴侣关系中的性行为方式或索引病例的临床状况有关。在考虑混杂因素后，伴侣关系持续≥1年的伴侣中HIV一致性风险增加（调整后的比值比为3.48；95%置信区间为0.89 - 13.69，P = 0.055），以及性伴侣有生殖器溃疡病史的伴侣中（针对卖淫进行调整：比值比为4.50；95%置信区间为1.01 - 20.4）。针对减少高危性行为、卖淫和可卡因使用的干预措施可能有助于减少特立尼达性传播疾病和HIV的传播。
