Hettling P
Tierarztl Prax Ausg K Kleintiere Heimtiere. 1998 Feb;26(1):37-9.
Analogous to the study of Onclin and Verstegen of 1996 the combination of a dopamine agonist, cabergoline, and a synthetic analogue of prostaglandin F2 alpha, cloprostenol or dinoprost, was used to induce termination of pregnancy 25 (+/- 2) days after the first mating. The study was done in six bitches. Cabergoline was administered at a dose of 5 micrograms/kg daily over a period of nine days and cloprostenol was injected subcutaneously at 1-2 micrograms/kg (dinoprost at a dose of 25 micrograms/kg) every other day. Treatment efficacy was 100%. No side effects were observed. Pregnancy and its termination was diagnosed by ultrasonographic examination. The combination of cabergoline and cloprostenol offers a simple and safe procedure for the termination of unwanted pregnancy.
与1996年Onclin和Verstegen的研究类似，使用多巴胺激动剂卡麦角林与前列腺素F2α的合成类似物氯前列醇或地诺前列素联合用药，在首次交配后25（±2）天诱导终止妊娠。该研究在6只母犬身上进行。卡麦角林以每天5微克/千克的剂量给药，持续9天，氯前列醇每隔一天皮下注射1 - 2微克/千克（地诺前列素剂量为25微克/千克）。治疗有效率为100%。未观察到副作用。通过超声检查诊断妊娠及其终止情况。卡麦角林和氯前列醇联合用药为终止意外妊娠提供了一种简单且安全的方法。
