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[阿奇霉素预防地中海斑疹热]

[Azithromycin in the prevention of Mediterranean spotted fever].

作者信息

Dzelalija B, Morović M, Avsic-Zupanc T

机构信息

Sluzba za lijecenje zaraznih bolesti, Opća bolnica Zadar.

出版信息

Lijec Vjesn. 1997 Nov;119(10):270-2.

PMID:9531759
Abstract

Antibodies to Rickettsia conorii were detected by the indirect immunofluorescence (IFA) assay in 64 (51.6%) out of 124 examinees living in North Dalmatia (Croatia) who had a history of recent tick bites during 1994 and 1995. Positive titers of IFA antibodies to R. conorii were detected in 12 (31.5%) out of 38 examinees with carried out prophylaxis by azithromycin. The usual clinical signs of Mediterranean spotted fever were registered in 22 (25.6%) and asymptomatic infection in 30 (34.8%) out of 86 examinees without prophylaxis. Clinical signs of the disease were not registered in examinees with prophylaxis.

摘要

在1994年和1995年期间有近期蜱叮咬史、居住在北达尔马提亚(克罗地亚)的124名受检者中,通过间接免疫荧光(IFA)检测发现,64人(51.6%)检测到康氏立克次体抗体。在38名接受阿奇霉素预防治疗的受检者中,12人(31.5%)检测到IFA抗康氏立克次体抗体呈阳性。在86名未接受预防治疗的受检者中,22人(25.6%)出现地中海斑疹热的常见临床症状,30人(34.8%)为无症状感染。接受预防治疗的受检者未出现该疾病的临床症状。

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