Onadeko M O, Joynson D H, Payne R A, Francis J
Department of Preventive and Social Medicine, University College Hospital, Ibadan, Nigeria.
Afr J Med Med Sci. 1996 Dec;25(4):331-4.
Toxoplasma antibody serological tests were carried out using the Dye test on sera of pregnant and postpartum Nigerian women to investigate whether there was any association between the levels of antibody titres and the occurrence of stillbirths and congenital malformations. There was a high prevalence of toxoplasma antibodies in the sera of both pregnant and postpartum women. The prevalence rates for the pregnant women ranged from 72.5% to 88.8% with an overall rate of 75.4%; whilst for the postpartum women, the prevalence rates ranged from 75.0% to 94.4% with an overall rate of 80.5%. The toxoplasma antibody titres of the sera from the live-born babies as well as stillbirths and congenitally malformed babies ranged from 1:16 to 1:1024. The exact role played by toxoplasma in the occurrence of stillbirths and congenital malformation in our area of study is, however, not clear. For future research, it is suggested that larger samples be studied in order to enhance the validity of the findings of the present study.
采用染料试验对尼日利亚孕妇和产后妇女的血清进行弓形虫抗体血清学检测，以调查抗体滴度水平与死产及先天性畸形的发生之间是否存在关联。孕妇和产后妇女血清中弓形虫抗体的患病率都很高。孕妇的患病率在72.5%至88.8%之间，总体患病率为75.4%；而产后妇女的患病率在75.0%至94.4%之间，总体患病率为80.5%。活产婴儿以及死产和先天性畸形婴儿血清中的弓形虫抗体滴度在1:16至1:1024之间。然而，在我们的研究区域，弓形虫在死产和先天性畸形发生中的确切作用尚不清楚。对于未来的研究，建议研究更大的样本，以提高本研究结果的有效性。
