Franklin D M, Dror Z, Nishri Z
Ministry of Health, Safed, Israel.
Isr J Med Sci. 1993 May;29(5):285-6.
A group of 213 pregnant Jewish women of Israeli and North-African/Asian origin in the Upper Gallilee in Israel were tested for Toxoplasma antibody, first at 4-12 weeks gestation and again 5-6 months later. Immunofluorescent antibody, Sabin-Feldman tests, and specific IgM estimation were used. The prevalence rates for seropositive women were lower in both groups (total 21%) than the rate found in a 1973 study in Israel. The incidence rate for infection acquired in pregnancy was 1.4%. There were no cases of congenital toxoplasmosis, as far as is known up to 3 years of age. More information on the prevalence and incidence of seropositivity, and on congenital toxoplasmosis, is required before a policy decision can be taken as to whether an antenatal screening program for toxoplasmosis should be instituted in Israel.
对以色列上加利利地区的213名以色列裔以及北非/亚洲裔犹太孕妇进行了弓形虫抗体检测，第一次检测在妊娠4至12周时进行，5至6个月后再次检测。采用了免疫荧光抗体检测、Sabin-Feldman检测以及特异性IgM测定。两组血清反应阳性女性的患病率均低于1973年以色列一项研究中的患病率（总计21%）。孕期感染的发病率为1.4%。据了解，直至3岁，未出现先天性弓形虫病病例。在就是否应在以色列开展弓形虫病产前筛查项目做出政策决定之前，需要更多关于血清反应阳性的患病率和发病率以及先天性弓形虫病的信息。
